Recombinant Human ALKBH5
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Cat.No.:REH- Q6P6C2 |
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Product Background |
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Recombinant Human Probable alpha-ketoglutarate-dependent dioxygenase ABH5(ALKBH5) |
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Enables mRNA N6-methyladenosine dioxygenase activity and molecular condensate scaffold activity. Involved in membraneless organelle assembly; post-transcriptional regulation of gene expression; and response to hypoxia. Acts upstream of or within regulation of mRNA export from nucleus and regulation of mRNA processing. Located in Golgi apparatus; cytosol; and nuclear speck. Is active in paraspeckles.Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro). |
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Product Information |
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Source |
E.coli |
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Molecular Weight |
48.2 kDa(2-394AA) |
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AA Sequence |
AAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGAKRKYQ EDSDPERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTV DRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFV NSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSV TVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDP ALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCSEA AGSPARKVKMRRH |
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Tag Information |
N-terminal 6xHis-tagged |
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Physical Appearance |
Liquid or Lyophilized powder |
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Formulation |
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
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Endotoxin |
Less than 1 EU/mg of Recombinant Protein as determined by LAL method. |
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Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
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Purity |
>90 % by SDS-PAGE. |
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Stability & Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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12 months from date of receipt, -20 to -80 °C as supplied. |
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1 month, 2 to 8 °C under sterile conditions after reconstitution. |
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3 months, -20 to -70 °C under sterile conditions after reconstitution. |
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Usage Information |
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This product is offered by InCellGen only for Scientific Research & Laboratory USE. NOT FOR OTHER USE. |
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Order Information |
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Quantity |
Price($） |
Price(�) |
Price(￥/CNY） |
Price(￥/JYP） |
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20ug |
$260.00 |
� 312.00 |
￥2,600.00 |
￥51,740.00 |
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100ug |
$505.00 |
� 606.00 |
￥5,050.00 |
￥100,495.00 |
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1mg |
$2,150.00 |
� 2,580.00 |
￥21,500.00 |
￥427,850.00 |
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Free Delivery on orders over $200.00. |
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We Devoted Ourselves To The Development Of Biomedical Research Reagent. |
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